Neo-adjuvant therapy in breast cancer

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[Neo-adjuvant chemotherapy for breast cancer].

OBJECTIVE To study the value and indications of a neo-adjuvant chemotherapy for breast cancers. METHODS Forty-three breast cancer patients were given the NF neo-adjuvant chemotherapy (Navelbine 25 mg/m2 and 5-Fu 500 mg/m2) for 3 cycles before the operation. Epirubicin (EPI 40 mg/m2) was added in patients with locally advanced lesions. G-CSF 75 micrograms subcutaneous injection was used to inc...

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Re-Challenging Taxanes in Recurrent Breast Cancer in Patients Treated with (Neo-)Adjuvant Taxane-Based Therapy.

SUMMARY: Background: Docetaxel and paclitaxel are among the most active substances for the treatment of breast cancer. As both drugs are used today in adjuvant regimens, efficacy data from pivotal trials in the metastatic setting in taxane-naive populations cannot reliably be used as references. Patients and Methods: The Taxane Re-Challenge Cohort Study identified participants from 6 prospectiv...

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Exploring patient experiences of neo-adjuvant chemotherapy for breast cancer.

BACKGROUND AND PURPOSE Neo-adjuvant chemotherapy is recommended for 'inoperable' locally advanced and inflammatory breast cancers. For operable breast cancers, trials indicate no survival differences between chemotherapy given pre or post-surgery. Communicating evidence based information to patients is complex and studies examining patient experiences of neo-adjuvant chemotherapy are lacking. T...

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Adjuvant therapy in primary breast cancer.

This article considers the role of adjuvant therapy in primary breast cancer, utilizing data from randomized prospective clinical trials as illustrative examples. The ongoing efforts targeted toward addressing some of the unresolved issues are underscored.

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Neo-adjuvant and adjuvant chemotherapy in bladder cancer.

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2005

ISSN: 0923-7534

DOI: 10.1093/annonc/mdi704